Longevity Clinics Hybrid
Rank 05
Human Longevity Executive Health
The original genome-plus-MRI clinic is still open in San Diego and South San Francisco, with a PNAS cohort and an SF Chronicle site visit — and still no mortality RCT.
Photograph by Steve Jurvetson, CC BY 2.0, via Flickr, resized
Why it is here
Catherine Ho of the San Francisco Chronicle (16 Jul 2025) toured the South San Francisco clinic, reported annual fees of $8,000–$19,000, and quoted Stanford geriatrician Deborah Kado and UCSF radiologist Rebecca Smith-Bindman on overdiagnosis risk; the company admitted it lacks longitudinal survival data versus the population. Perkins et al. in PNAS (2020) described the Health Nucleus self-referred cohort (n=1,190): 17.3% pathogenic or likely-pathogenic variants, 1.7% early-stage tumors, 34.2% insulin resistance, 29.2% elevated liver fat — observational, not an RCT, and with no mortality endpoint. The clinic FAQ fetched 3 Sep 2026 lists Executive Health at $8,000 for under-65 ($12,000 100+ Care; $19,000 100+ Concierge). The $1 million cancer pledge is a marketing contract, not outcomes research.
Who it is for
Clients who want a one-day genome plus whole-body MRI with a named clinician review, and who accept that the outcome evidence is observational.
Sources
- $19,000 a year for a longer life?Reporter toured South SF clinic; annual fees $8k–$19k; Stanford geriatrician Deborah Kado and UCSF radiologist Rebecca Smith-Bindman warn of overdiagnosis; company admits it lacks longitudinal survival data vs population.
- Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imagingHealth Nucleus self-referred cohort n=1,190; 17.3% pathogenic/likely-pathogenic variant; 1.7% early-stage tumors; 34.2% insulin resistance; 29.2% elevated liver fat. Not an RCT.
- Executive HealthExecutive Health Assessment is $8,000; under-65 product. 100+ Care $12,000; 100+ Concierge $19,000.
